Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.46 |
| ▸ | CCR4 | P51679 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036678 | 0.92 | CA12 (0.47) | EPHX2P2RX7CA12CA1CA2 | |
| SCHEMBL4035552 | 0.90 | P2RX7 (0.51) | EPHX2P2RX7 | |
| SCHEMBL4032375 | 0.87 | CA12 (0.46) | EPHX2P2RX7CA12CA1CA2 | |
| SCHEMBL4033312 | 0.87 | P2RX7 (0.45) | EPHX2P2RX7 | |
| SCHEMBL4033086 | 0.86 | MMP1 (0.50) | EPHX2GAASMN1; SMN2P2RX7 | |
| SCHEMBL4037666 | 0.86 | ALDH1A1 (0.52) | EPHX2TSHRP2RX7CCR4 | |
| SCHEMBL4038771 | 0.84 | P2RX7 (0.45) | EPHX2SMN1; SMN2P2RX7 | |
| SCHEMBL4038132 | 0.83 | MMP1 (0.44) | SMN1; SMN2P2RX7 | |
| SCHEMBL4032675 | 0.82 | GAA (0.48) | GAASMN1; SMN2 | |
| SCHEMBL4034716 | 0.81 | P2RX7 (0.42) | EPHX2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |