Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035088 | 0.86 | CHRNB2 (0.42) | GAACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL4026248 | 0.84 | ALDH1A1 (0.45) | GAACHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL4031887 | 0.75 | CYP3A4 (0.54) | ALDH1A1 | |
| SCHEMBL6480554 | 0.74 | ALDH1A1 (0.59) | GAAHPGDALDH1A1LMNAKDM4E | |
| SCHEMBL4031087 | 0.74 | ALDH1A1 (0.59) | GAAHPGDALDH1A1LMNAKDM4E | |
| SCHEMBL6492319 | 0.74 | ALDH1A1 (0.59) | GAAHPGDALDH1A1LMNAKDM4E | |
| SCHEMBL17350908 | 0.72 | ALDH1A1 (0.53) | POLBHPGDALDH1A1LMNAHIF1A | |
| SCHEMBL10243899 | 0.72 | ALDH1A1 (0.53) | POLBHPGDALDH1A1LMNAHIF1A | |
| SCHEMBL1909477 | 0.71 | GAA (0.58) | GAAPOLBHPGDALDH1A1LMNA | |
| P-Anisic Acid SCHEMBL27396257 | 0.70 | CA1 (0.71) | GAAPOLBALDH1A1LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452527-B1 | AZABICYCLO COMPOUND, MATRIX METALLOPROTEASE INHIBITOR, AND SKIN PREPARATION | SHISEIDO CO LTD (JP) | 2009-03-04 | — | — | EP | disclosed |
| US-7176217-B2 | Azabicyclo compound matrix metalloprotease inhibitor and skin preparation | SHISEIDO CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| US-20050009808-A1 | Azabicyclo compound matrix metalloprotease inibitor and skin preparation | SHISEIDO CO., LTD. (JP) | 2005-01-13 | — | — | US | disclosed |
| EP-1452527-A1 | AZABICYCLO COMPOUND, MATRIX METALLOPROTEASE INHIBITOR, AND SKIN PREPARATION | Shiseido Co., Ltd. (JP) | 2004-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009808-A1 | Azabicyclo compound matrix metalloprotease inibitor and skin preparation | MMP1, MMP16, MMP9 | GAA 1852/4885CHRNB2 2163/4885CHRNB4 3577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.