Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 7/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825818 | 0.96 | XIAP (0.40) | LMNATP53XIAPATMTRPA1 | |
| SCHEMBL4040107 | 0.90 | ATM (0.41) | LMNATP53XIAPATMTRPA1 | |
| SCHEMBL3952543 | 0.89 | TDP1 (0.41) | LMNATP53XIAPATMTRPA1 | |
| SCHEMBL3890621 | 0.89 | PKM (0.40) | LMNATP53ATMTRPA1KMT2A | |
| SCHEMBL4834382 | 0.83 | MAPT (0.41) | LMNATP53XIAPATMTRPA1 | |
| SCHEMBL4842641 | 0.82 | GNRHR (0.39) | LMNATP53ATMTRPA1PTGER3 | |
| SCHEMBL4030551 | 0.82 | LMNA (0.40) | LMNATP53ATMPTGER3KMT2A | |
| SCHEMBL3820156 | 0.81 | LMNA (0.43) | LMNATP53XIAPATMTRPA1 | |
| SCHEMBL4035980 | 0.81 | TRPA1 (0.43) | TRPA1RORCGCGRMMP3MMP8 | |
| SCHEMBL4038964 | 0.79 | ALDH1A1 (0.42) | LMNATP53XIAPATMTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885695-B1 | INDOLINE COMPOUNDS | FOURNIER LAB SA (FR) | 2009-02-25 | — | — | EP | disclosed |