Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 11/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | XIAP | P98170 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039085 | 0.92 | ATM (0.45) | ATMTRPA1LMNAL3MBTL1TP53 | |
| SCHEMBL3820156 | 0.88 | LMNA (0.43) | ATMTRPA1LMNAXIAPL3MBTL1 | |
| SCHEMBL3825818 | 0.84 | XIAP (0.40) | ATMTRPA1LMNAXIAPL3MBTL1 | |
| SCHEMBL4840572 | 0.83 | LMNA (0.41) | TRPA1LMNAXIAPTP53RORC | |
| SCHEMBL4842724 | 0.82 | TRPA1 (0.40) | TRPA1LMNAXIAPTP53RORC | |
| SCHEMBL4031790 | 0.81 | TRPA1 (0.46) | ALDH1A1MAPTTRPA1LMNARORC | |
| SCHEMBL4841061 | 0.80 | ATM (0.45) | ATMTRPA1LMNAL3MBTL1TP53 | |
| SCHEMBL4837872 | 0.80 | MMP8 (0.45) | ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL4032871 | 0.79 | LMNA (0.39) | MAPK1ATMTRPA1LMNAXIAP | |
| SCHEMBL4033992 | 0.79 | RAB9A (0.44) | ALDH1A1MAPTATMTRPA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885695-B1 | INDOLINE COMPOUNDS | FOURNIER LAB SA (FR) | 2009-02-25 | — | — | EP | disclosed |
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | ALDH1A1 1819/4885MAPT 763/4885MAPK1 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.