Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 13/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 10/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.40 |
| ▸ | GABRP | O00591 | 7/20 | 0.40 |
| ▸ | GABRD | O14764 | 7/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 7/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.40 |
| ▸ | GABRE | P78334 | 7/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 7/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 7/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 7/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5220202 | 0.83 | GABRB3 (0.42) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL4852573 | 0.82 | RAB9A (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL14209955 | 0.77 | GABRP (0.45) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL4039283 | 0.77 | GABRP (0.41) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL4854540 | 0.76 | GABRP (0.41) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL28073555 | 0.76 | GABRB3 (0.46) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL2001797 | 0.74 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL20577971 | 0.74 | BACE1 (0.51) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7713408 | 0.73 | BACE1 (0.50) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7089578 | 0.73 | GABRB3 (0.46) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976737-B1 | PYRAZOLE DERIVATIVES, PROCESS FOR PREPARING THE SAME, INTERMEDIATES, AND PEST CONTROL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | NIHON NOHYAKU CO LTD (JP) | 2009-06-10 | — | — | EP | disclosed |
| US-6335357-B1 | 1-ARYL-3-CYANO-5-(HET)ARYLALKYLAMINOPYRAZOLE DERIVATIVES; INSECTICIDES FOR AGRICULTURE AND HORTICULTURE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-01-01 | — | — | US | disclosed |
| EP-0976737-A1 | PYRAZOLE DERIVATIVES, PROCESS FOR PREPARING THE SAME, INTERMEDIATES, AND PEST CONTROL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-02-02 | — | — | EP | disclosed |