Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 8/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031721 | 0.90 | HTR1A (0.39) | MPOHTR1ASLC6A4ANO1ADAM17 | |
| SCHEMBL4035538 | 0.86 | ADAM17 (0.38) | MPOHTR1ASLC6A4ANO1ADAM17 | |
| SCHEMBL13902849 | 0.85 | MPO (0.46) | MPOHTR1ASLC6A4ADAM17SPR | |
| SCHEMBL3934460 | 0.85 | MPO (0.46) | MPOHTR1ASLC6A4ADAM17SPR | |
| SCHEMBL4034241 | 0.82 | ADAM17 (0.36) | MPOHTR1ASLC6A4ANO1ADAM17 | |
| SCHEMBL4029370 | 0.81 | HTR1A (0.42) | MPOHTR1ASLC6A4ANO1SPR | |
| SCHEMBL4033961 | 0.81 | MPO (0.41) | MPOHTR1ASLC6A4ADAM17SPR | |
| SCHEMBL3938249 | 0.80 | MPO (0.43) | MPOHTR1ASLC6A4ADAM17SPR | |
| SCHEMBL13902845 | 0.80 | MPO (0.43) | MPOHTR1ASLC6A4ADAM17SPR | |
| SCHEMBL4033975 | 0.80 | MAPT (0.39) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |