Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NMBR | P28336 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4037073 | 0.90 | KMT2A (0.39) | MAPTKMT2AMEN1TACR1CYP2D6 | |
| SCHEMBL4035462 | 0.89 | KMT2A (0.41) | MAPTKMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL4038448 | 0.85 | KMT2A (0.42) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3939353 | 0.84 | MEN1 (0.42) | MAPTKMT2AMEN1HCRTR1KDM4E | |
| SCHEMBL4033976 | 0.81 | MEN1 (0.39) | MAPTKMT2AMEN1HCRTR1KDM4E | |
| SCHEMBL4033972 | 0.81 | MEN1 (0.39) | MAPTKMT2AMEN1HCRTR1KDM4E | |
| SCHEMBL4031864 | 0.81 | MAPT (0.40) | MAPTKMT2AMEN1NMBRTACR1 | |
| SCHEMBL4033963 | 0.80 | MPO (0.46) | CYP2D6 | |
| SCHEMBL4034270 | 0.80 | KMT2A (0.46) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3945226 | 0.80 | MMP9 (0.40) | MAPTKMT2AMEN1HCRTR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |