Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CKS1B | P61024 | 3/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035674 | 0.86 | KMT2A (0.34) | ALDH1A1KMT2ALMNATDP1MAPT | |
| SCHEMBL4032848 | 0.86 | RAB9A (0.37) | ALDH1A1LMNAHTTSLC40A1TSHR | |
| SCHEMBL4816387 | 0.78 | ALDH1A1 (0.35) | ALDH1A1KMT2ALMNATDP1MAPT | |
| SCHEMBL4030515 | 0.76 | TDP1 (0.52) | ALDH1A1KMT2ALMNATDP1CKS1B | |
| SCHEMBL14269080 | 0.75 | LMNA (0.38) | ALDH1A1KMT2ALMNATDP1CKS1B | |
| SCHEMBL4027701 | 0.69 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNATDP1CKS1B | |
| SCHEMBL14269082 | 0.65 | LMNA (0.34) | ALDH1A1LMNAHTTSLC40A1TSHR | |
| SCHEMBL14269064 | 0.65 | RCE1 (0.35) | ALDH1A1KMT2ALMNAMAPTHTT | |
| SCHEMBL4031312 | 0.63 | SLC40A1 (0.42) | ALDH1A1KMT2ALMNATDP1MAPT | |
| SCHEMBL7369637 | 0.62 | DDB1 (0.47) | ALDH1A1KMT2ALMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307454-B1 | DERIVATIVES OF VARIOLIN B | PHARMA MAR SA (ES) | 2009-06-03 | — | — | EP | disclosed |