Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032848 | 0.91 | RAB9A (0.37) | TP53RAB9ASLC40A1NPC1LMNA | |
| SCHEMBL4034210 | 0.86 | ALDH1A1 (0.40) | KMT2ATP53MAPTMEN1SLC40A1 | |
| SCHEMBL4816387 | 0.81 | ALDH1A1 (0.35) | KMT2ATP53MAPTMEN1TDP1 | |
| SCHEMBL4029308 | 0.77 | MEN1 (0.47) | KMT2ATP53MAPTMEN1RAB9A | |
| SCHEMBL14269084 | 0.75 | SLC40A1 (0.35) | KMT2ATP53MAPTMEN1RAB9A | |
| SCHEMBL4031970 | 0.71 | SLC40A1 (0.46) | KMT2AMAPTMEN1RAB9ASLC40A1 | |
| SCHEMBL4031312 | 0.68 | SLC40A1 (0.42) | KMT2ATP53MAPTMEN1RAB9A | |
| SCHEMBL14269082 | 0.67 | LMNA (0.34) | TP53RAB9ASLC40A1SCN8ASCN1A | |
| SCHEMBL14269064 | 0.67 | RCE1 (0.35) | KMT2ATP53MAPTMEN1RAB9A | |
| SCHEMBL14269080 | 0.64 | LMNA (0.38) | KMT2ATP53MAPTMEN1SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307454-B1 | DERIVATIVES OF VARIOLIN B | PHARMA MAR SA (ES) | 2009-06-03 | — | — | EP | disclosed |