Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.32 |
| ▸ | HRH1 | P35367 | 5/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13797859 | 0.85 | PTGS2 (0.31) | — | |
| SCHEMBL817028 | 0.79 | MAOA (0.38) | MAOA | |
| SCHEMBL13797871 | 0.78 | — | — | |
| SCHEMBL7546246 | 0.65 | ACHE (0.37) | HTR2AGPR3 | |
| SCHEMBL7048563 | 0.65 | GPR3 (0.43) | HTR2AGPR3 | |
| SCHEMBL6671925 | 0.64 | GPR3 (0.46) | HTR2AGPR3 | |
| SCHEMBL30390148 | 0.64 | GPR3 (0.46) | HTR2AGPR3 | |
| SCHEMBL5981387 | 0.64 | GPR3 (0.46) | HTR2AGPR3 | |
| SCHEMBL5175634 | 0.64 | GPR3 (0.46) | HTR2AGPR3 | |
| SCHEMBL817343 | 0.64 | CES1 (0.41) | HTR2AHRH1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009149906-A2 | PREPARATION OF SILOXY-BRIDGED METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2009-12-17 | — | — | WO | disclosed |
| US-7544825-B1 | Preparation of siloxy-bridged metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2009-06-09 | — | — | US | disclosed |
| US-7544825-B1 | Preparation of siloxy-bridged metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2009-06-09 | — | — | US | disclosed |