Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | GPR3 | P46089 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3479971 | 0.82 | ACHE (0.38) | ACHEBCHEHTR2AGPR3POLB | |
| SCHEMBL7542344 | 0.74 | HTR2A (0.31) | HTR2ATSHRALDH1A1HTR2CHTR2B | |
| SCHEMBL7048563 | 0.73 | GPR3 (0.43) | ACHEBCHEHTR2AGPR3POLB | |
| SCHEMBL6671925 | 0.72 | GPR3 (0.46) | ACHEBCHEHTR2AGPR3POLB | |
| SCHEMBL30390148 | 0.72 | GPR3 (0.46) | ACHEBCHEHTR2AGPR3POLB | |
| SCHEMBL5981387 | 0.72 | GPR3 (0.46) | ACHEBCHEHTR2AGPR3POLB | |
| SCHEMBL5175634 | 0.72 | GPR3 (0.46) | ACHEBCHEHTR2AGPR3POLB | |
| SCHEMBL2551833 | 0.72 | ACHE (0.40) | ACHEBCHEHTR2AGPR3POLB | |
| SCHEMBL8086443 | 0.71 | GPR3 (0.41) | ACHEBCHEHTR2AGPR3POLB | |
| SCHEMBL7583449 | 0.71 | GPR3 (0.41) | ACHEBCHEHTR2AGPR3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997042165-A1 | FLUORENE SUBSTITUTED WITH A GROUP COMPRISING A HETERO ATOM | DSM N.V. (NL) | 1997-11-13 | — | — | WO | claimed |
| EP-0693497-B1 | Process for the preparation of silicon-bridged asymmetric cyclopentadienyl-, indenyl- and fluorenyl-containing ligand systems | BOREALIS TECH OY (FI) | 2002-06-12 | — | — | EP | disclosed |
| WO-1997042165-A1 | FLUORENE SUBSTITUTED WITH A GROUP COMPRISING A HETERO ATOM | DSM N.V. (NL) | 1997-11-13 | — | — | WO | disclosed |
| EP-0693497-A2 | Process for the preparation of silicon-bridged asymmetric cyclopentadienyl-, indenyl- and fluorenyl-containing ligand systems | PCD-Polymere Gesellschaft m.b.H. (AT) | 1996-01-24 | — | — | EP | disclosed |