Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026147 | 0.94 | FEN1 (0.39) | FEN1ERCC1ERCC4 | |
| SCHEMBL4026142 | 0.79 | FEN1 (0.57) | FEN1ERCC1ERCC4 | |
| SCHEMBL4027681 | 0.78 | ERCC1 (0.41) | FEN1ERCC1ERCC4 | |
| SCHEMBL4028795 | 0.76 | ERCC1 (0.39) | FEN1ERCC1ERCC4L3MBTL1 | |
| SCHEMBL4031565 | 0.74 | CXCR2 (0.39) | FEN1ERCC1ERCC4MAOAMAOB | |
| SCHEMBL4028369 | 0.73 | MEN1 (0.43) | FEN1ERCC1ERCC4L3MBTL1 | |
| SCHEMBL4032043 | 0.73 | ERCC1 (0.67) | FEN1ERCC1ERCC4L3MBTL1 | |
| SCHEMBL4026226 | 0.72 | MAOB (0.38) | FEN1ERCC1ERCC4L3MBTL1MAOB | |
| SCHEMBL4028226 | 0.72 | MAPK10 (0.42) | FEN1ERCC1ERCC4 | |
| SCHEMBL4027166 | 0.72 | MEN1 (0.37) | FEN1ERCC1ERCC4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470113-B1 | PYRIMIDINONE VIRAL POLYMERASE INHIBITORS | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-01-07 | — | — | EP | claimed |