Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14713221 | 0.94 | TSHR (0.48) | TSHRPPARDTP53TDP1 | |
| SCHEMBL2351297 | 0.92 | TSHR (0.46) | TSHRPPARD | |
| SCHEMBL5201343 | 0.87 | TSHR (0.54) | TSHRPPARDTP53TDP1 | |
| SCHEMBL17124976 | 0.82 | TSHR (0.38) | TSHRPPARDTP53TDP1 | |
| SCHEMBL5017294 | 0.79 | PPARD (0.64) | TSHRPPARDTP53TDP1 | |
| SCHEMBL7268189 | 0.79 | PPARD (0.64) | TSHRPPARDTP53TDP1 | |
| SCHEMBL6187009 | 0.79 | TSHR (0.50) | TSHRPPARDTP53TDP1 | |
| SCHEMBL11514496 | 0.77 | PPARD (0.61) | TSHRPPARDTP53TDP1 | |
| SCHEMBL11323349 | 0.77 | PPARD (0.61) | TSHRPPARDTP53TDP1 | |
| SCHEMBL7268183 | 0.77 | PPARD (0.61) | TSHRPPARDTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3126517-B1 | MODIFIED CYTOSINE POLYNUCLEOTIDE OLIGOMERS AND METHODS | CEPHEID (US) | 2019-10-23 | — | — | EP | disclosed |
| US-9598455-B2 | Modified thymine polynucleotide oligomers and methods | CEPHEID (US) | 2017-03-21 | — | — | US | disclosed |
| US-9598456-B2 | Modified cytosine polynucleotide oligomers and methods | CEPHEID (US) | 2017-03-21 | — | — | US | disclosed |
| US-9598455-B2 | Modified thymine polynucleotide oligomers and methods | CEPHEID (US) | 2017-03-21 | — | — | US | disclosed |
| US-9598456-B2 | Modified cytosine polynucleotide oligomers and methods | CEPHEID (US) | 2017-03-21 | — | — | US | disclosed |
| EP-2591354-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2016-09-07 | — | — | EP | disclosed |
| EP-2591354-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2016-09-07 | — | — | EP | disclosed |
| WO-2015153496-A1 | MODIFIED THYMINE POLYNUCLEOTIDE OLIGOMERS AND METHODS | CEPHEID (US) | 2015-10-08 | — | — | WO | disclosed |
| WO-2015153510-A1 | MODIFIED CYTOSINE POLYNUCLEOTIDE OLIGOMERS AND METHODS | CEPHEID (US) | 2015-10-08 | — | — | WO | disclosed |
| US-20150275283-A1 | MODIFIED CYTOSINE POLYNUCLEOTIDE OLIGOMERS AND METHODS | CEPHEID (US) | 2015-10-01 | — | — | US | disclosed |
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | CANNIZZARO CARINA | 2009-10-01 | — | — | US | disclosed |
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | CANNIZZARO CARINA | 2009-10-01 | — | — | US | disclosed |
| US-20090131372-A1 | PHOSPHONATE ANALOGS FOR TREATING METABOLIC DISEASES | CHEN JAMES M | 2009-05-21 | — | — | US | disclosed |
| US-7432261-B2 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432261-B2 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432261-B2 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. (US) | 2008-10-07 | — | — | US | disclosed |
| US-7407965-B2 | Phosphonate analogs for treating metabolic diseases | GILEAD SCIENCES, INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-20060199788-A1 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. | 2006-09-07 | — | — | US | disclosed |
| EP-1663254-A2 | ANTI-INFLAMATORY PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2004100960-A2 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2004-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | PHOSPHO1, TNF, PTGES | TSHR 4758/4885PPARD 197/4885TP53 3241/4885 |
| US-20090131372-A1 | PHOSPHONATE ANALOGS FOR TREATING METABOLIC DISEASES | PHOSPHO1, G6PC1, PC | TSHR 2537/4885PPARD 334/4885TP53 2042/4885 |
| US-20150275283-A1 | MODIFIED CYTOSINE POLYNUCLEOTIDE OLIGOMERS AND METHODS | POLN, POLI, POLRMT | TSHR 4567/4885PPARD 2554/4885TP53 733/4885 |
| US-20060199788-A1 | Anti-inflammatory phosphonate compounds | PHOSPHO1, TNF, PTGES | TSHR 4758/4885PPARD 197/4885TP53 3241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.