Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 3/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031158 | 0.91 | MEN1 (0.43) | LPAR1LPAR2LPAR3MEN1KMT2A | |
| SCHEMBL4030241 | 0.89 | LPAR1 (0.42) | LPAR1LPAR2LPAR3LMNAALDH1A1 | |
| SCHEMBL4034939 | 0.88 | LPAR1 (0.45) | LPAR1LPAR2LPAR3MEN1KMT2A | |
| SCHEMBL4032394 | 0.87 | LPAR1 (0.47) | LPAR1LPAR2LPAR3MEN1KMT2A | |
| SCHEMBL4036696 | 0.87 | LPAR1 (0.44) | LPAR1LPAR2LPAR3MEN1KMT2A | |
| SCHEMBL4032913 | 0.85 | LPAR1 (0.42) | LPAR1LPAR2LPAR3MEN1LMNA | |
| SCHEMBL4028841 | 0.85 | LPAR1 (0.43) | LPAR1LPAR2LPAR3MEN1LMNA | |
| SCHEMBL4034918 | 0.83 | LPAR1 (0.45) | LPAR1LPAR2LPAR3 | |
| SCHEMBL4032920 | 0.83 | ATM (0.44) | LPAR1LPAR2LPAR3MEN1KMT2A | |
| SCHEMBL4034499 | 0.83 | LPAR1 (0.48) | LPAR1LPAR2LPAR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1258484-B1 | NOVEL ISOXAZOLE AND THIAZOLE COMPOUNDS AND USE THEREOF AS DRUGS | KYOWA HAKKO KIRIN CO LTD (JP) | 2009-01-14 | — | — | EP | claimed |