Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.53 |
| ▸ | MMP3 | P08254 | 7/20 | 0.53 |
| ▸ | MMP7 | P09237 | 7/20 | 0.53 |
| ▸ | MMP9 | P14780 | 7/20 | 0.53 |
| ▸ | MMP13 | P45452 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4037009 | 0.87 | ALDH1A1 (0.52) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL4039378 | 0.85 | MMP1 (0.52) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL4041974 | 0.79 | GAA (0.51) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL4041721 | 0.79 | GAA (0.51) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL4034808 | 0.79 | GAA (0.51) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL4033586 | 0.79 | ALDH1A1 (0.55) | GAAALDH1A1 | |
| SCHEMBL4036877 | 0.79 | ALDH1A1 (0.52) | GAAALDH1A1 | |
| SCHEMBL4035716 | 0.78 | ALDH1A1 (0.46) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL4036675 | 0.77 | ALDH1A1 (0.51) | GAAALDH1A1 | |
| SCHEMBL4036852 | 0.77 | MMP1 (0.50) | MMP1MMP3MMP7MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |