SCHEMBL4037636

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4037440	0.88	GPR132 (0.43)	LMNAMAPTGPR132RAB9ANPC1
	SCHEMBL4048563	0.86	HDAC1 (0.40)	GPR132DPP4PREP
	SCHEMBL4046192	0.86	LMNA (0.40)	CTSKLMNAALDH1A1MAPTHTT
	SCHEMBL4038260	0.83	CTSK (0.38)	CTSKLMNAALDH1A1MAPTHTT
	SCHEMBL4043534	0.81	CTSK (0.39)	CTSKLMNAALDH1A1MAPTHTT
	SCHEMBL4047880	0.80	CTSK (0.48)	CTSKLMNAALDH1A1GAAMEN1
	SCHEMBL4043502	0.80	TNKS (0.39)	ALDH1A1MAPTMEN1KMT2ANAMPT
	SCHEMBL4041333	0.80	CTSK (0.69)	CTSKLMNAALDH1A1MAPTHTT
	SCHEMBL4037811	0.79	CTSK (0.57)	CTSKLMNAALDH1A1MAPTHTT
	SCHEMBL4049108	0.79	CTSK (0.57)	CTSKLMNAALDH1A1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.