Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041978 | 0.87 | CNR2 (0.35) | PARP1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL4214923 | 0.85 | ALDH1A1 (0.37) | PARP1KDM4ELMNAMAPTTGFBR1 | |
| SCHEMBL4034813 | 0.84 | PKM (0.43) | PARP1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL4036107 | 0.84 | PDE5A (0.36) | PARP1KDM4ETGFBR1PDE5ATDP1 | |
| SCHEMBL2053105 | 0.83 | PARP1 (0.43) | PARP1KIF11KDM4ELMNAMAPT | |
| SCHEMBL4041261 | 0.83 | RHEB (0.44) | PARP1KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL4036257 | 0.83 | TUBB4A (0.43) | PARP1KDM4ELMNAMAPTTGFBR1 | |
| SCHEMBL4036172 | 0.83 | PDE5A (0.35) | PARP1KDM4ETGFBR1PDE5AKMT2A | |
| SCHEMBL4035502 | 0.82 | TUBB4A (0.39) | PARP1LMNAPDE5AMEN1KMT2A | |
| SCHEMBL4033284 | 0.81 | PTGS1 (0.37) | PARP1KDM4ELMNAPDE5AICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747220-B1 | SUBSTITUTED 1H-PYRROLO[3,2-B, 3,2-C, AND 2,3-C]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON | AVENTIS PHARMA INC (US) | 2009-04-15 | — | — | EP | claimed |