Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.39 |
| ▸ | TUBB | P07437 | 4/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 4/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033192 | 0.91 | PKN1 (0.38) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4035489 | 0.89 | SLC6A4 (0.43) | MEN1KMT2APARP1SLC6A4PTGDR2 | |
| SCHEMBL4032967 | 0.89 | SMN1; SMN2 (0.41) | MEN1KMT2APDE5ASLC6A4PTGDR2 | |
| SCHEMBL4036370 | 0.87 | PARP1 (0.37) | MEN1KMT2APARP1PDE5AJAK2 | |
| SCHEMBL4033284 | 0.86 | PTGS1 (0.37) | PARP1PDE5AJAK2LMNAALDH1A1 | |
| SCHEMBL4036827 | 0.86 | KDM4E (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4043268 | 0.86 | PKN1 (0.36) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4033058 | 0.86 | TYMS (0.37) | MEN1KMT2AJAK2ALDH1A1 | |
| SCHEMBL4035517 | 0.86 | TYMS (0.37) | JAK2LMNAALDH1A1 | |
| SCHEMBL4034008 | 0.86 | LMNA (0.37) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747220-B1 | SUBSTITUTED 1H-PYRROLO[3,2-B, 3,2-C, AND 2,3-C]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON | AVENTIS PHARMA INC (US) | 2009-04-15 | — | — | EP | claimed |