Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | TACR1 | P25103 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | NMBR | P28336 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035462 | 0.89 | KMT2A (0.41) | KMT2AMEN1TACR1CYP2D6KDM4E | |
| SCHEMBL4037073 | 0.87 | KMT2A (0.39) | KMT2AMEN1TACR1CYP2D6MAPT | |
| SCHEMBL4034270 | 0.86 | KMT2A (0.46) | KMT2AMEN1TACR1KDM4EAPAF1 | |
| SCHEMBL4033975 | 0.85 | MAPT (0.39) | KMT2AMEN1TACR1CYP2D6KDM4E | |
| SCHEMBL3941814 | 0.84 | MEN1 (0.42) | KMT2AMEN1TACR1KDM4EAPAF1 | |
| SCHEMBL4031864 | 0.83 | MAPT (0.40) | KMT2AMEN1TACR1POLBMAPT | |
| SCHEMBL13904509 | 0.82 | MMP9 (0.43) | KMT2AMEN1TACR1CYP2D6KDM4E | |
| SCHEMBL3947792 | 0.82 | MMP9 (0.43) | KMT2AMEN1TACR1CYP2D6KDM4E | |
| SCHEMBL4055562 | 0.82 | TACR1 (0.46) | KMT2AMEN1TACR1TACR3NMBR | |
| SCHEMBL4062789 | 0.79 | TACR1 (0.44) | KMT2AMEN1TACR1CYP2D6TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |