Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 7/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | NMBR | P28336 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5149351 | 0.86 | ANO1 (0.41) | KMT2AMEN1KDM4ETACR1KCNA5 | |
| SCHEMBL4038448 | 0.86 | KMT2A (0.42) | KMT2AMEN1KDM4EPOLBAPAF1 | |
| SCHEMBL4035462 | 0.84 | KMT2A (0.41) | KMT2AMEN1KDM4EPOLBAPAF1 | |
| SCHEMBL4037073 | 0.82 | KMT2A (0.39) | KMT2AMEN1MAPTTACR1TACR3 | |
| SCHEMBL3939262 | 0.81 | MEN1 (0.46) | KMT2AMEN1KDM4EPOLBAPAF1 | |
| SCHEMBL4033975 | 0.80 | MAPT (0.39) | KMT2AMEN1KDM4EMAPTRECQL | |
| SCHEMBL4029965 | 0.79 | CDK4 (0.47) | KMT2AMEN1MAPTNMBRALDH1A1 | |
| SCHEMBL4031864 | 0.78 | MAPT (0.40) | KMT2AMEN1POLBMAPTTACR1 | |
| SCHEMBL4169038 | 0.78 | ITGB2 (0.45) | KMT2AMEN1KDM4EPOLBAPAF1 | |
| SCHEMBL3944251 | 0.78 | CTSL (0.45) | KMT2AMEN1KDM4EPOLBAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |