Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 4/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.36 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19309525 | 0.86 | ITGB3 (0.41) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL9215328 | 0.84 | ITGB3 (0.42) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL12352492 | 0.78 | TPSAB1 (0.41) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL3469238 | 0.77 | CA2 (0.43) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL1775192 | 0.77 | ATM (0.39) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL423784 | 0.75 | CA2 (0.45) | TPSAB1TPSD1TPSG1ITGB3ITGA2B | |
| SCHEMBL21888390 | 0.75 | TPSAB1 (0.49) | TPSAB1TPSD1TPSG1CA2CA12 | |
| SCHEMBL25138081 | 0.75 | TPSAB1 (0.40) | TPSAB1TPSD1TPSG1CA2CA12 | |
| SCHEMBL4434497 | 0.74 | SIGMAR1 (0.53) | TPSAB1TPSD1TPSG1GAA | |
| SCHEMBL1775928 | 0.74 | GNAI3 (0.42) | TPSAB1TPSD1TPSG1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | claimed |
| EP-2041103-A2 | DERIVATIVES OF UREA AND RELATED DIAMINES, METHODS FOR THEIR MANUFACTURE, AND USES THEREFOR | Galapagos SAS (FR) | 2009-04-01 | — | — | EP | claimed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | claimed |
| WO-2008006625-A2 | DERIVATIVES OF UREA AND RELATED DIAMINES, METHODS FOR THEIR MANUFACTURE, AND USES THEREFOR | GALAPAGOS SAS (FR) | 2008-01-17 | — | — | WO | claimed |
| US-5756765-A | BACTERICIDES AND ANTIBIOTICS | CHONG KUN DANG CORP. (KR) | 1998-05-26 | — | — | US | claimed |
| US-5641770-A | THIENAMYCINS ANTIBIOTICS | CHONG KUN DANG CORP. (KR) | 1997-06-24 | — | — | US | claimed |