Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4441326 | 0.97 | — | — | |
| Bromide SCHEMBL3225071 | 0.94 | TRIM24 (0.37) | TRIM24TRIM33ALDH1A1LMNACHRM2 | |
| Hydrochloric Acid SCHEMBL3732793 | 0.94 | TRIM24 (0.37) | TRIM24TRIM33ALDH1A1LMNACHRM2 | |
| SCHEMBL8352753 | 0.84 | TRIM24 (0.30) | TRIM24TRIM33 | |
| Trifluoromethanesulfonic Acid SCHEMBL8388996 | 0.75 | ACHE (0.33) | — | |
| SCHEMBL4836270 | 0.73 | — | — | |
| Iodide SCHEMBL11340215 | 0.71 | — | — | |
| SCHEMBL739073 | 0.69 | TRIM24 (0.32) | TRIM24TRIM33ALDH1A1 | |
| Bromide SCHEMBL4087944 | 0.67 | TRIM24 (0.30) | TRIM24TRIM33 | |
| Iodide SCHEMBL4706138 | 0.67 | MEN1 (0.33) | KDM4EMEN1POLBAPOBEC3APMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070243221-A1 | ANTI-WRINKLE COMPOSITION | L'OREAL (FR) | 2007-10-18 | — | — | US | claimed |
| EP-4603480-A1 | INDOLE PHTHALOCYANINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN TUMOR DIAGNOSIS IMAGING | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2025-08-20 | — | — | EP | disclosed |
| US-20250059159-A1 | PLPRO INHIBITORS | HUAHAI US INC. | 2025-02-20 | — | — | US | disclosed |
| EP-4448515-A1 | PLPRO INHIBITORS | Shanghai Synergy Pharmaceutical Sciences Co., Ltd (CN) | 2024-10-23 | — | — | EP | disclosed |
| US-20240325547-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-10-03 | — | — | US | disclosed |
| CN-113473987-B | Substituted 3- ((3-aminophenyl) amino) piperidine-2, 6-dione compounds, compositions thereof, and methods of treatment using the same | 细胞基因公司 | 2024-09-03 | — | — | CN | disclosed |
| US-20240246070-A1 | PIPERIDINIUM-CONTAINING ANION EXCHANGE POLYMERS | VERSOGEN, INC. | 2024-07-25 | — | — | US | disclosed |
| US-11986532-B2 | Modulators of BCL6 proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2024-05-21 | — | — | US | disclosed |
| CN-112638898-B | Heteroaryl substituted sulfonamide compounds and their use as sodium channel inhibitors | 泽农医药公司 | 2024-04-09 | — | — | CN | disclosed |
| EP-4323352-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |
| US-20020019531-A1 | Indoles | EISAI CO., LTD. | 2002-02-14 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |
| EP-0976732-A1 | 1,4-SUBSTITUTED CYCLIC AMINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| US-5756508-A | Muscarine antagonists | MERCK & CO., INC. (US) | 1998-05-26 | — | — | US | disclosed |
| US-5691323-A | BENZIMIDAZOL-2-ONES | MERCK & CO., INC. (US) | 1997-11-25 | — | — | US | disclosed |
| US-5668153-A | Piperidine derivatives and their use as therapeutic agents | MERCK SHARP & DOHME, LTD. (GB) | 1997-09-16 | — | — | US | disclosed |
| WO-1997016192-A1 | MUSCARINE ANTAGONISTS | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | disclosed |
| WO-1996013262-A1 | MUSCARINE ANTAGONISTS | MERCK & CO., INC. (US) | 1996-05-09 | — | — | WO | disclosed |
| WO-1993014084-A2 | PIPERIDINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019531-A1 | Indoles | INMT, MUSK, MB | CHRM1 16/4885CHRM3 146/4885TRIM24 841/4885 |
| US-20070243221-A1 | ANTI-WRINKLE COMPOSITION | NR2C2, FFAR3, NR1I2 | CHRM1 32/4885CHRM3 61/4885TRIM24 2804/4885 |
| US-11986532-B2 | Modulators of BCL6 proteolysis and associated methods of use | BCL6, BCL6B, BCL3 | CHRM1 4742/4885CHRM3 4680/4885TRIM24 917/4885 |
| US-20250059159-A1 | PLPRO INHIBITORS | SARS1, PLP2, PLPBP | CHRM1 4689/4885CHRM3 4220/4885TRIM24 444/4885 |
| US-20240325547-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | BCL6, BCL6B, BCL3 | CHRM1 4742/4885CHRM3 4680/4885TRIM24 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.