Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL410306 | 0.97 | TSHR (0.39) | ALDH1A1TSHRHMGCRCHRM1TBXA2R | |
| SCHEMBL15208490 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL11686332 | 0.79 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL3035945 | 0.75 | — | — | |
| SCHEMBL2517858 | 0.73 | TSHR (0.35) | ALDH1A1TSHRHMGCRCHRM1TBXA2R | |
| SCHEMBL2552626 | 0.73 | HDAC6 (0.35) | — | |
| SCHEMBL15312738 | 0.72 | — | — | |
| SCHEMBL5394152 | 0.72 | — | — | |
| SCHEMBL286191 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL345565 | 0.71 | TSHR (0.42) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1555265-B1 | 7-PHENYL PYRAZOLOPYRIDINE COMPOUNDS | EISAI R&D MAN CO LTD (JP) | 2009-03-25 | — | — | EP | disclosed |
| US-20080076943-A1 | 7-PHENYLPYRAZOLOPYRIDINE COMPOUNDS | HIBI SHIGEKI | 2008-03-27 | — | — | US | disclosed |
| US-7323569-B2 | 7-phenylpyrazolopyridine compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-01-29 | — | — | US | disclosed |
| US-7211589-B2 | Atisane compounds and use thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-05-01 | — | — | US | disclosed |
| US-7176216-B2 | 7-phenylpyrazolopyridine compounds | EISAI CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| US-20060235011-A1 | 7-Phenyl pyrazolopyridine compounds | EISAI CO.LTD. (JP) | 2006-10-19 | — | — | US | disclosed |
| EP-1555265-A1 | 7-PHENYL PYRAZOLOPYRIDINE COMPOUNDS | Eisai Co., Ltd. (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-20040224974-A1 | 7-phenylpyrazolopyridine compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-11-11 | — | — | US | disclosed |
| US-20040180930-A1 | Novel atisane compounds and use thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1382591-A1 | NOVEL ATISANE COMPOUND AND USE THEREOF | Eisai Co., Ltd. (JP) | 2004-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224974-A1 | 7-phenylpyrazolopyridine compounds | CRHR1, MC2R, CRH | ALDH1A1 2616/4885TSHR 118/4885HMGCR 3415/4885 |
| US-20080076943-A1 | 7-PHENYLPYRAZOLOPYRIDINE COMPOUNDS | MC2R, CRHR1, CRHR2 | ALDH1A1 3348/4885TSHR 80/4885HMGCR 3543/4885 |
| US-20040180930-A1 | Novel atisane compounds and use thereof | GRIN1, SLC1A2, GRIN3A | ALDH1A1 415/4885TSHR 2058/4885HMGCR 2142/4885 |
| US-20060235011-A1 | 7-Phenyl pyrazolopyridine compounds | MC2R, CRHR1, CRHR2 | ALDH1A1 3334/4885TSHR 67/4885HMGCR 3651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.