Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.40 |
| ▸ | CTSL | P07711 | 4/20 | 0.40 |
| ▸ | CTSV | O60911 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 7/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052113 | 0.90 | CTSK (0.41) | CTSSCTSLCTSKCTSB | |
| SCHEMBL4042622 | 0.90 | CTSS (0.40) | CTSSCTSLCTSVCTSKCTSB | |
| SCHEMBL4044073 | 0.89 | CTSK (0.33) | CTSK | |
| SCHEMBL4046220 | 0.89 | CTSK (0.36) | CTSSCTSLCTSK | |
| SCHEMBL6238379 | 0.88 | CTSL (0.48) | CTSSCTSLCTSVCTSKCTSB | |
| SCHEMBL4047132 | 0.88 | CTSS (0.39) | CTSSCTSLCTSVCTSKCTSB | |
| SCHEMBL4047616 | 0.85 | CTSL (0.46) | CTSSCTSLCTSVCTSKCTSB | |
| SCHEMBL4043598 | 0.83 | CTSS (0.37) | CTSSCTSLCTSVCTSKCTSB | |
| SCHEMBL4043817 | 0.83 | CTSL (0.39) | CTSSCTSLCTSVCTSK | |
| SCHEMBL4050085 | 0.82 | CTSS (0.40) | CTSSCTSLCTSVCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |