Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.41 |
| ▸ | CTSL | P07711 | 7/20 | 0.35 |
| ▸ | CTSS | P25774 | 5/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046220 | 0.92 | CTSK (0.36) | CTSKCTSLCTSS | |
| SCHEMBL4044073 | 0.92 | CTSK (0.33) | CTSK | |
| SCHEMBL4043552 | 0.90 | CTSS (0.40) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4047763 | 0.89 | CTSK (0.44) | CTSKCTSLCTSSCTSBMEN1 | |
| SCHEMBL4047629 | 0.89 | CTSK (0.40) | CTSKCTSLCTSSCTSBMEN1 | |
| SCHEMBL4044439 | 0.88 | CTSK (0.41) | CTSKCTSLCTSSCTSBMEN1 | |
| SCHEMBL4046098 | 0.86 | CTSK (0.39) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4049409 | 0.86 | CTSK (0.42) | CTSKCTSLCTSSCTSBMEN1 | |
| SCHEMBL4043679 | 0.84 | CTSK (0.46) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4041781 | 0.84 | CTSK (0.39) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |