Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044073 | 0.93 | CTSK (0.33) | CTSK | |
| SCHEMBL4052113 | 0.92 | CTSK (0.41) | CTSKCTSLCTSS | |
| SCHEMBL4043552 | 0.89 | CTSS (0.40) | CTSKCTSLCTSS | |
| SCHEMBL4040755 | 0.89 | CTSK (0.35) | CTSKCTSLCTSS | |
| SCHEMBL4047188 | 0.88 | CTSK (0.36) | CTSK | |
| SCHEMBL4047540 | 0.84 | CTSK (0.47) | CTSKCTSLCTSS | |
| SCHEMBL4042603 | 0.83 | CTSK (0.35) | CTSK | |
| SCHEMBL4040745 | 0.82 | HSD17B10 (0.36) | CTSKCTSLCTSS | |
| SCHEMBL4041133 | 0.82 | CTSK (0.36) | CTSK | |
| SCHEMBL4048544 | 0.82 | P2RY12 (0.32) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |