Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.40 |
| ▸ | CTSL | P07711 | 6/20 | 0.37 |
| ▸ | CTSS | P25774 | 4/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043393 | 0.93 | FKBP1A (0.35) | CTSKCTSSCTSBCHRNB2CHRNA7 | |
| SCHEMBL4037989 | 0.90 | CTSK (0.42) | CTSKCTSLCTSSCTSBCHRNB2 | |
| SCHEMBL4043952 | 0.89 | CTSK (0.42) | CTSKCTSLCTSSCTSBCHRNA7 | |
| SCHEMBL4045331 | 0.88 | CTSK (0.43) | CTSKCTSLCTSSCTSBCHRNB2 | |
| SCHEMBL4042904 | 0.88 | CTSK (0.39) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4045898 | 0.88 | CTSK (0.41) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4043196 | 0.88 | CTSK (0.39) | CTSKCTSLCTSSCTSBFKBP1A | |
| SCHEMBL4045035 | 0.87 | CTSK (0.45) | CTSKCTSLCTSSCTSBCHRNB2 | |
| SCHEMBL4042866 | 0.87 | CTSK (0.50) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4050222 | 0.86 | CTSK (0.43) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |