Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.42 |
| ▸ | CTSL | P07711 | 6/20 | 0.39 |
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043998 | 0.92 | FKBP1A (0.37) | CTSKCTSSCTSBCHRNA7FKBP1A | |
| SCHEMBL4050147 | 0.92 | CTSK (0.40) | CTSKCTSLCTSSCTSBFKBP1A | |
| SCHEMBL4045511 | 0.90 | F2 (0.38) | CTSKCTSSCTSB | |
| SCHEMBL4047615 | 0.90 | CTSB (0.38) | CTSKCTSSCTSBCHRNA7FKBP1A | |
| SCHEMBL4042866 | 0.89 | CTSK (0.50) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4051777 | 0.89 | CTSK (0.44) | CTSKCTSLCTSSCTSBCHRNA7 | |
| SCHEMBL4044003 | 0.89 | CTSK (0.40) | CTSKCTSLCTSSCTSBCHRNA7 | |
| SCHEMBL4050328 | 0.89 | SCN9A (0.39) | CTSKCTSSCTSBCHRNA7FKBP1A | |
| SCHEMBL4048306 | 0.89 | CTSK (0.38) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4042764 | 0.89 | CTSK (0.38) | CTSKCTSLCTSSCTSBFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |