Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043459 | 0.90 | CTSK (0.41) | CTSKKDM4E | |
| SCHEMBL4048376 | 0.88 | CTSK (0.51) | CTSKCTSS | |
| SCHEMBL4037609 | 0.85 | CTSK (0.31) | CTSK | |
| SCHEMBL4044452 | 0.85 | CTSK (0.39) | CTSK | |
| SCHEMBL4050761 | 0.83 | PIK3CD (0.42) | CTSK | |
| SCHEMBL4044693 | 0.82 | CTSK (0.42) | CTSKKMT2ACTSS | |
| SCHEMBL4044247 | 0.81 | CTSK (0.39) | CTSKMEN1KMT2A | |
| SCHEMBL4044364 | 0.80 | AKR1C3 (0.31) | — | |
| SCHEMBL4042992 | 0.80 | CTSK (0.39) | CTSK | |
| SCHEMBL4040766 | 0.79 | CTSK (0.40) | CTSKKDM4ECTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |