Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043459 | 0.85 | CTSK (0.41) | CTSK | |
| SCHEMBL4048376 | 0.85 | CTSK (0.51) | CTSK | |
| SCHEMBL4049285 | 0.85 | CTSK (0.41) | CTSK | |
| SCHEMBL4042644 | 0.83 | CTSK (0.33) | CTSK | |
| SCHEMBL4040766 | 0.80 | CTSK (0.40) | CTSKCCR8KCNH2 | |
| SCHEMBL4044693 | 0.80 | CTSK (0.42) | CTSKCCR8KCNH2 | |
| SCHEMBL4042992 | 0.79 | CTSK (0.39) | CTSK | |
| SCHEMBL4050761 | 0.79 | PIK3CD (0.42) | CTSK | |
| SCHEMBL4044247 | 0.78 | CTSK (0.39) | CTSK | |
| SCHEMBL4228919 | 0.78 | CTSK (0.38) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |