Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23667966 | 0.81 | LMNA (0.46) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4049990 | 0.80 | LMNA (0.45) | LMNAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL4045697 | 0.80 | LMNA (0.45) | LMNAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL6734438 | 0.80 | LMNA (0.45) | LMNAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL4752981 | 0.80 | LMNA (0.45) | LMNAKMT2APOLB | |
| SCHEMBL4753368 | 0.80 | ALDH1A1 (0.45) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4751039 | 0.79 | ALDH1A1 (0.45) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4751059 | 0.77 | MEN1 (0.41) | LMNAALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL21588776 | 0.77 | KDM4E (0.40) | ALDH1A1SMN1; SMN2KMT2AMEN1RECQL | |
| SCHEMBL29814593 | 0.77 | KDM4E (0.40) | ALDH1A1SMN1; SMN2KMT2AMEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576224-B2 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives | FMC CORPORATION (US) | 2009-08-18 | — | — | US | disclosed |
| US-7576224-B2 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives | FMC CORPORATION (US) | 2009-08-18 | — | — | US | disclosed |
| US-7576224-B2 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives | FMC CORPORATION (US) | 2009-08-18 | — | — | US | disclosed |
| EP-1620421-B1 | INSECTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED DIHYDROBENZOFURAN AND DIHYDROBENZOPYRAN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-06-24 | — | — | EP | disclosed |
| EP-1620421-A4 | INSECTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED DIHYDROBENZOFURAN AND DIHYDROBENZOPYRAN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-10-31 | — | — | EP | disclosed |
| US-20060094776-A1 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives | FMC CORPORATION | 2006-05-04 | — | — | US | disclosed |
| EP-1620421-A2 | INSECTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED DIHYDROBENZOFURAN AND DIHYDROBENZOPYRAN DERIVATIVES | FMC CORPORATION (US) | 2006-02-01 | — | — | EP | disclosed |
| US-6987194-B2 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives | FMC CORPORATION (US) | 2006-01-17 | — | — | US | disclosed |
| WO-2004098283-A2 | INSECTICIDAL (DIHALOPROPENYL) PHENYLALKYL SUBSTITUTED DIHYDROBENZOFURAN AND DIHYDROBENZOPYRAN DERIVATIVES | FMC CORPORATION (US) | 2004-11-18 | — | — | WO | disclosed |
| US-20040224994-A1 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives | FMC CORPORATION | 2004-11-11 | — | — | US | disclosed |
| US-20040186170-A1 | Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient | EGIS GYOGYSZERGYAR (HU) | 2004-09-23 | — | — | US | disclosed |
| EP-1077973-A2 | BENZOFURAN DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND A PROCESS FOR THE PREPARATION OF THE ACTIVE INGREDIENT | EGIS GYOGYSZERGYAR RT. (HU) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058527-A2 | BENZOFURAN DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND A PROCESS FOR THE PREPARATION OF THE ACTIVE INGREDIENT | EGIS Gyógyszergyár Rt. (HU) | 1999-11-18 | — | — | WO | disclosed |
| US-4560682-A | INSECTICIDES, MITICIDES | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1985-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224994-A1 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives | DDT, DHCR24, RPS24 | LMNA 4436/4885ALDH1A1 370/4885SMN1; SMN2 3926/4885 |
| US-20040186170-A1 | Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient | CYP2F1, CYP3A4, CYP2S1 | LMNA 2499/4885ALDH1A1 81/4885SMN1; SMN2 3211/4885 |
| US-20060094776-A1 | Insecticidal (dihalopropenyl) phenylalkyl substituted dihydrobenzofuran and dihydrobenzopyran derivatives | DDT, DHCR24, L3MBTL1 | LMNA 4255/4885ALDH1A1 480/4885SMN1; SMN2 3889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.