Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TLR3 | O15455 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751039 | 0.94 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2TSHRTDP1 | |
| SCHEMBL4751070 | 0.88 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2NPC1KMT2A | |
| SCHEMBL4751068 | 0.88 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2NPC1KMT2A | |
| SCHEMBL4750825 | 0.86 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2NPC1KMT2A | |
| SCHEMBL4750822 | 0.85 | CHRNB2 (0.44) | ALDH1A1LMNASMN1; SMN2NPC1KMT2A | |
| SCHEMBL4753173 | 0.84 | MAPT (0.41) | ALDH1A1LMNASMN1; SMN2NPC1KMT2A | |
| SCHEMBL6734151 | 0.81 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2NPC1KMT2A | |
| SCHEMBL4044524 | 0.80 | LMNA (0.42) | ALDH1A1LMNASMN1; SMN2NPC1KMT2A | |
| SCHEMBL4753309 | 0.79 | NPC1 (0.37) | ALDH1A1LMNANPC1KMT2AMAPT | |
| SCHEMBL4750827 | 0.76 | ALDH1A1 (0.38) | ALDH1A1LMNASMN1; SMN2NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146063-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-12-04 | — | — | WO | disclosed |