Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049257 | 0.92 | CTSK (0.41) | CTSKUTS2R | |
| SCHEMBL4040945 | 0.90 | CTSK (0.31) | CTSK | |
| SCHEMBL4050225 | 0.90 | CTSK (0.35) | CTSKUTS2RPREPFAPELANE | |
| SCHEMBL4045249 | 0.89 | CTSK (0.36) | CTSKP2RY12ELANE | |
| SCHEMBL4051650 | 0.88 | HSD17B10 (0.36) | CTSKPREPFAP | |
| SCHEMBL4046677 | 0.88 | CTSK (0.34) | CTSKP2RY12 | |
| SCHEMBL4044695 | 0.86 | CTSK (0.36) | CTSKP2RY12 | |
| SCHEMBL4051242 | 0.86 | CTSK (0.33) | CTSKP2RY12PREPFAPELANE | |
| SCHEMBL4049444 | 0.85 | PREP (0.33) | CTSKP2RY12PREPFAPELANE | |
| SCHEMBL4043984 | 0.85 | CTSK (0.39) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |