Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049345 | 0.93 | CTSK (0.38) | CTSK | |
| SCHEMBL4042623 | 0.92 | CTSV (0.32) | CTSK | |
| SCHEMBL4044587 | 0.90 | CTSK (0.35) | CTSK | |
| SCHEMBL4039885 | 0.89 | KDM4E (0.32) | CTSK | |
| SCHEMBL4043270 | 0.89 | CTSK (0.32) | CTSK | |
| SCHEMBL4043056 | 0.89 | HSD17B10 (0.36) | — | |
| SCHEMBL4041176 | 0.85 | CTSL (0.36) | CTSK | |
| SCHEMBL4046677 | 0.85 | CTSK (0.34) | CTSK | |
| SCHEMBL4047785 | 0.85 | CTSK (0.32) | CTSK | |
| SCHEMBL4044695 | 0.84 | CTSK (0.36) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678157-A4 | HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THEREOF | REDDY US THERAPEUTICS INC (US) | 2009-03-18 | — | — | EP | disclosed |
| EP-1678157-A2 | HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THEREOF | Reddy US Therapeutics, Inc. (US) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042712-A2 | HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THEREOF | REDDY US THERAPEUTICS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |