Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039525 | 0.92 | CTSK (0.42) | CTSKELANECCR4LMNA | |
| SCHEMBL4044695 | 0.92 | CTSK (0.36) | CTSKP2RY12 | |
| SCHEMBL4043292 | 0.91 | ALDH1A1 (0.37) | CTSKP2RY12LMNA | |
| SCHEMBL4049558 | 0.89 | CTSK (0.36) | CTSKELANECCR1TGM2 | |
| SCHEMBL4048294 | 0.89 | ALDH1A1 (0.37) | LMNAHPGD | |
| SCHEMBL4044587 | 0.89 | CTSK (0.35) | CTSKELANEP2RY12 | |
| SCHEMBL4049444 | 0.88 | PREP (0.33) | CTSKELANEP2RY12 | |
| SCHEMBL4044730 | 0.88 | LMNA (0.39) | CTSKCCR1LMNA | |
| SCHEMBL4051242 | 0.88 | CTSK (0.33) | CTSKELANEP2RY12 | |
| SCHEMBL4047785 | 0.87 | CTSK (0.32) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |