Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.33 |
| ▸ | CTSL | P07711 | 13/20 | 0.33 |
| ▸ | CTSS | P25774 | 9/20 | 0.33 |
| ▸ | CTSB | P07858 | 3/20 | 0.33 |
| ▸ | CTSV | O60911 | 2/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042413 | 0.93 | CTSK (0.40) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4043383 | 0.92 | TAS1R3 (0.35) | — | |
| SCHEMBL4047816 | 0.90 | CTSK (0.33) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4045579 | 0.89 | HPGD (0.32) | — | |
| SCHEMBL4041999 | 0.89 | HSD17B10 (0.36) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6240769 | 0.88 | CTSK (0.43) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4045249 | 0.88 | CTSK (0.36) | CTSKP2RY12ELANE | |
| SCHEMBL4046811 | 0.87 | CTSK (0.33) | CTSKP2RY12PREPFAP | |
| SCHEMBL4044587 | 0.86 | CTSK (0.35) | CTSKP2RY12PREPFAPELANE | |
| SCHEMBL4045411 | 0.86 | PREP (0.33) | CTSKP2RY12PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |