Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13905292 | 0.84 | PDE9A (0.35) | METAP2METAP1 | |
| SCHEMBL4053441 | 0.77 | ADORA3 (0.40) | METAP2METAP1 | |
| SCHEMBL4052403 | 0.75 | METAP2 (0.36) | METAP2METAP1 | |
| SCHEMBL4047123 | 0.75 | METAP2 (0.36) | METAP2METAP1 | |
| SCHEMBL4044144 | 0.72 | METAP2 (0.34) | METAP2METAP1 | |
| SCHEMBL4046994 | 0.71 | ADORA1 (0.42) | METAP2METAP1 | |
| SCHEMBL4052252 | 0.68 | KDM4C (0.41) | METAP2METAP1 | |
| SCHEMBL20570034 | 0.67 | HCAR2 (0.49) | METAP2METAP1 | |
| SCHEMBL4046172 | 0.67 | METAP2 (0.35) | METAP2METAP1 | |
| SCHEMBL4053122 | 0.66 | GPR84 (0.47) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009029592-A1 | HETEROBICYCLIC-SUBSTITUTED QUINOLONES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | KALYPSYS, INC. (US) | 2009-03-05 | — | — | WO | disclosed |
| WO-2009029592-A1 | HETEROBICYCLIC-SUBSTITUTED QUINOLONES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | KALYPSYS, INC. (US) | 2009-03-05 | — | — | WO | disclosed |