Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | BCL9 | O00512 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | PPID | Q08752 | 2/20 | 0.47 |
| ▸ | PPIB | P23284 | 1/20 | 0.47 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | PPIG | Q13427 | 1/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3156693 | 0.87 | CHRM2 (0.54) | CHRM2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL2045374 | 0.85 | PPID (0.67) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8172847 | 0.84 | RAB9A (0.53) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14128576 | 0.82 | CHRM2 (0.49) | LMNACHRM2MEN1KMT2AMAPT | |
| SCHEMBL8252663 | 0.82 | SMN1; SMN2 (0.54) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11187635 | 0.82 | PPID (0.54) | LMNACHRM2KMT2AMAPTALDH1A1 | |
| SCHEMBL21794783 | 0.81 | LMNA (0.44) | LMNACHRM2MEN1KMT2AMAPT | |
| SCHEMBL27640326 | 0.81 | LMNA (0.49) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8229648 | 0.81 | LMNA (0.48) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL398701 | 0.80 | LMNA (0.73) | LMNAMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |