Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 4/20 | 0.39 |
| ▸ | BCR | P11274 | 4/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052779 | 0.90 | HDAC2 (0.49) | HDAC2HDAC3HDAC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28462863 | 0.75 | NFE2L2 (0.46) | SMN1; SMN2ALDH1A1NPC1RAB9AGAA | |
| SCHEMBL4049840 | 0.74 | HDAC3 (0.47) | HDAC2HDAC3HDAC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4326042 | 0.73 | HDAC3 (0.43) | HDAC2HDAC3HDAC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4452303 | 0.71 | HTR1A (0.60) | HDAC2HDAC3HDAC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13626256 | 0.71 | HTR1A (0.60) | HDAC2HDAC3HDAC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30584126 | 0.71 | HDAC2 (0.55) | HDAC2HDAC3HDAC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28505528 | 0.71 | HDAC2 (0.55) | HDAC2HDAC3HDAC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4052776 | 0.69 | ABL1 (0.50) | HDAC2HDAC3HDAC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3438289 | 0.67 | ERN1 (0.54) | HDAC2ALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109504-A1 | ENOL CARBAMATE DERIVATIVES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-09-11 | — | — | WO | disclosed |