Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.50 |
| ▸ | BCR | P11274 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049840 | 0.89 | HDAC3 (0.47) | ABL1BCRHDAC1HDAC3HDAC2 | |
| SCHEMBL4051643 | 0.81 | KMT2A (0.60) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL764236 | 0.78 | ABL1 (0.76) | ABL1BCRHDAC1HDAC3HDAC2 | |
| SCHEMBL10198116 | 0.76 | ABL1 (0.76) | ABL1BCRHDAC1HDAC3HDAC2 | |
| SCHEMBL4052779 | 0.74 | HDAC2 (0.49) | ABL1BCRHDAC1HDAC3HDAC2 | |
| SCHEMBL4051880 | 0.73 | KMT2A (0.52) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL8002050 | 0.70 | POLB (0.44) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL4452303 | 0.70 | HTR1A (0.60) | ABL1BCRHDAC1HDAC3HDAC2 | |
| SCHEMBL13626256 | 0.70 | HTR1A (0.60) | ABL1BCRHDAC1HDAC3HDAC2 | |
| SCHEMBL27577342 | 0.69 | SMN1; SMN2 (0.44) | ABL1BCRHDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109504-A1 | ENOL CARBAMATE DERIVATIVES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009109504-A1 | ENOL CARBAMATE DERIVATIVES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2009-09-11 | — | — | WO | disclosed |