Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970741 | 0.88 | ALDH1A3 (0.61) | SMN1; SMN2LMNAALDH1A1MAPTHPGD | |
| SCHEMBL11789545 | 0.88 | ALDH1A3 (0.61) | SMN1; SMN2LMNAALDH1A1MAPTHPGD | |
| SCHEMBL4058956 | 0.82 | ALDH1A1 (0.57) | RAB9ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL4053086 | 0.82 | ALDH1A1 (0.57) | RAB9ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL4048710 | 0.81 | ALDH1A1 (0.53) | RAB9ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL9421468 | 0.81 | LMNA (0.57) | RAB9ASMN1; SMN2LMNAMAPTL3MBTL1 | |
| SCHEMBL23223734 | 0.80 | RAB9A (0.69) | RAB9ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL11614936 | 0.80 | RAB9A (0.69) | RAB9ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL4054280 | 0.79 | SMN1; SMN2 (0.75) | RAB9ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL13462927 | 0.79 | SMN1; SMN2 (0.75) | RAB9ASMN1; SMN2LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |