Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5001507 | 0.72 | L3MBTL1 (0.67) | TSHRL3MBTL1MCOLN3ACHELMNA | |
| SCHEMBL4047383 | 0.72 | L3MBTL1 (0.67) | TSHRL3MBTL1MCOLN3ACHELMNA | |
| SCHEMBL6346703 | 0.72 | L3MBTL1 (0.67) | TSHRL3MBTL1MCOLN3ACHELMNA | |
| SCHEMBL6891702 | 0.71 | ALDH1A1 (0.35) | USP2MCOLN3SMN1; SMN2GAALMNA | |
| SCHEMBL24278496 | 0.70 | ALDH1A1 (0.39) | TSHRL3MBTL1GAAKMT2AALDH1A1 | |
| SCHEMBL31717331 | 0.70 | TRPV4 (0.39) | L3MBTL1MCOLN3SMN1; SMN2GAALMNA | |
| SCHEMBL21962890 | 0.68 | ALDH1A1 (0.46) | MAPK1SMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL17065538 | 0.67 | MEN1 (0.60) | TSHRL3MBTL1GAALMNAKMT2A | |
| SCHEMBL1567289 | 0.67 | MAOA (0.35) | L3MBTL1MCOLN3SMN1; SMN2GAALMNA | |
| SCHEMBL4001419 | 0.67 | NPSR1 (0.51) | L3MBTL1MAPK1GAAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461315-B1 | CATALYTIC CARBONYLATION OF THREE AND FOUR MEMBERED HETEROCYCLES | CORNELL RES FOUNDATION INC (US) | 2009-07-29 | — | — | EP | disclosed |