Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454361 | 0.82 | MAPT (0.46) | ALDH1A1TRPA1HSD17B10LMNATSHR | |
| SCHEMBL2230553 | 0.81 | NPC1 (0.48) | ALDH1A1HPGDKDM4ELMNANPC1 | |
| SCHEMBL26385190 | 0.81 | NPC1 (0.48) | ALDH1A1HPGDKDM4ELMNANPC1 | |
| SCHEMBL143227 | 0.79 | ALDH1A1 (0.34) | ALDH1A1TRPA1GABRA1GABRB2HPGD | |
| SCHEMBL20171110 | 0.78 | CYP1A2 (0.50) | ALDH1A1HPGDCA2CYP1A2HIF1A | |
| SCHEMBL3879398 | 0.76 | TRPA1 (0.45) | ALDH1A1TRPA1GABRA1GABRB2HPGD | |
| SCHEMBL11707890 | 0.76 | KDM4E (0.38) | ALDH1A1HSD17B10KDM4ELMNATSHR | |
| SCHEMBL19848459 | 0.74 | SIGMAR1 (0.39) | ALDH1A1HPGDKDM4EATMNPC1 | |
| SCHEMBL11406581 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TRPA1GABRA1GABRB2HPGD | |
| SCHEMBL1004808 | 0.74 | ALDH1A1 (0.40) | ALDH1A1TRPA1LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2020252-A1 | Process for colouring and permanent shaping keratin fibres | KPSS-Kao Professional Salon Services GmbH (DE) | 2009-02-04 | — | — | EP | disclosed |