Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050803 | 0.92 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL3653439 | 0.79 | MEN1 (0.65) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL4058118 | 0.78 | ALDH1A1 (0.60) | KMT2AALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL26313592 | 0.75 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL4059272 | 0.75 | ALDH1A1 (0.63) | KMT2AALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL7021479 | 0.75 | SMN1; SMN2 (0.64) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL18767163 | 0.74 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL4049726 | 0.74 | MAPT (0.52) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4049720 | 0.74 | MAPT (0.52) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2852902 | 0.73 | KMT2A (0.52) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111260-A1 | PHENYLSULFONAMIDE-SUBSTITUTED, PYRAZOLO[1, 5-A]PYRIMIDINES, METHODS FOR PREPARATION AND USES THEREOF | WYETH (US) | 2009-09-11 | — | — | WO | disclosed |