Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Trifluoromethanesulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL1294404 | 0.94 | CA2 (0.37) | GPR3CA1CA2CA7CA13 | |
| Lithium Ion SCHEMBL29507646 | 0.94 | CA2 (0.37) | GPR3CA1CA2CA7CA13 | |
| Potassium Ion SCHEMBL1294546 | 0.94 | CA2 (0.37) | GPR3CA1CA2CA7CA13 | |
| SCHEMBL6909339 | 0.88 | CA2 (0.37) | GPR3CA1CA2CA7CA13 | |
| SCHEMBL6912636 | 0.88 | CA2 (0.37) | GPR3CA1CA2CA7CA13 | |
| SCHEMBL732960 | 0.88 | CA2 (0.37) | GPR3CA1CA2CA7CA13 | |
| Zinc Ion SCHEMBL734146 | 0.88 | CA2 (0.37) | GPR3CA1CA2CA7CA13 | |
| SCHEMBL20873158 | 0.88 | CA2 (0.37) | GPR3CA1CA2CA7CA13 | |
| SCHEMBL21549837 | 0.88 | CA2 (0.37) | GPR3CA1CA2CA7CA13 | |
| SCHEMBL6915614 | 0.88 | CA2 (0.37) | GPR3CA1CA2CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397471-A4 | FUNCTIONAL FLUIDS WITH SERVO VALVE EROSION RESISTANCE | EXXONMOBIL RES & ENG CO (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-1397471-A1 | FUNCTIONAL FLUIDS WITH SERVO VALVE EROSION RESISTANCE | ExxonMobil Research and Engineering Company (US) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002086035-A1 | FUNCTIONAL FLUIDS WITH SERVO VALVE EROSION RESISTANCE | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2002-10-31 | — | — | WO | disclosed |