Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16398773 | 0.85 | MAOA (0.38) | CCKBRMEN1KMT2AALDH1A1AKT1 | |
| SCHEMBL22455608 | 0.82 | MEN1 (0.47) | CCKBRMEN1KMT2A | |
| SCHEMBL38655898 | 0.80 | MEN1 (0.39) | CCKBRMEN1KMT2AHTR6MAPT | |
| SCHEMBL5871195 | 0.80 | LMNA (0.40) | CCKBRMEN1KMT2AHTR6TACR2 | |
| SCHEMBL4057480 | 0.80 | PAX8 (0.39) | CCKBRMEN1KMT2AGSK3BHTR6 | |
| SCHEMBL4052811 | 0.77 | MYC (0.56) | MEN1KMT2ARAB9A | |
| SCHEMBL5871406 | 0.77 | PAX8 (0.53) | MEN1KMT2APAX8 | |
| SCHEMBL1688323 | 0.74 | CCKBR (0.42) | CCKBRMEN1KMT2AAKT1HRH2 | |
| SCHEMBL4053230 | 0.73 | MYC (0.57) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL4049317 | 0.72 | SMN1; SMN2 (0.47) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |