Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 2/20 | 0.56 |
| ▸ | MAX | P61244 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | NAT1 | P18440 | 5/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 2/20 | 0.52 |
| ▸ | MMP13 | P45452 | 2/20 | 0.52 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 2/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.48 |
| ▸ | CTSD | P07339 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051735 | 0.77 | CCKBR (0.38) | RAB9AMEN1KMT2A | |
| SCHEMBL4053230 | 0.77 | MYC (0.57) | MYCMAXRAB9AMEN1KMT2A | |
| SCHEMBL8176997 | 0.76 | NAT1 (0.75) | MYCMAXRAB9ANPC1NAT1 | |
| SCHEMBL8176998 | 0.76 | NAT1 (0.75) | MYCMAXRAB9ANPC1NAT1 | |
| SCHEMBL4416451 | 0.73 | NAT1 (1.00) | MYCMAXRAB9ANAT1CA2 | |
| SCHEMBL3491175 | 0.73 | NAT1 (1.00) | MYCMAXRAB9ANAT1CA2 | |
| SCHEMBL1812224 | 0.73 | NAT1 (1.00) | MYCMAXRAB9ANAT1CA2 | |
| SCHEMBL346693 | 0.73 | MYC (1.00) | MYCMAXRAB9ANPC1NAT1 | |
| SCHEMBL346694 | 0.73 | MYC (1.00) | MYCMAXRAB9ANPC1NAT1 | |
| SCHEMBL10042186 | 0.73 | MYC (1.00) | MYCMAXRAB9ANPC1NAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |