SCHEMBL4053226

SCHEMBL4053226

C=C(C)C(=O)OCCCCCCCCCCCC.C=C(C)C(=O)OCCO

nearest known ligand 0.86

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.86
THRB P10828 2/20 0.50
NAAA Q02083 1/20 0.48
HTT P42858 2/20 0.48
POLB P06746 1/20 0.48
APEX1 P27695 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
RAD52 P43351 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
EPHX1 P07099 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPT P10636 1/20 0.46
ALDH1A1 P00352 1/20 0.44
ACHE P22303 7/20 0.44
CES2 O00748 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8007369 1.00 TSHR (0.86) TSHRTHRBNAAAHTTPOLB
SCHEMBL7198622 1.00 TSHR (0.86) TSHRTHRBNAAAHTTPOLB
SCHEMBL11402168 1.00 TSHR (0.86) TSHRTHRBNAAAHTTPOLB
Propanol SCHEMBL17472935 0.95 TSHR (0.89) TSHRTHRBNAAAHTTPOLB
Ethylene Glycol SCHEMBL10600183 0.95 TSHR (0.89) TSHRTHRBNAAAHTTPOLB
Ethylene Glycol SCHEMBL27514805 0.95 TSHR (0.89) TSHRTHRBNAAAHTTPOLB
Ethylene Glycol SCHEMBL20263739 0.95 TSHR (0.89) TSHRTHRBNAAAHTTPOLB
Hexane SCHEMBL1449723 0.94 TSHR (0.75) TSHRTHRBNAAAHTTPOLB
Di(Hydroxyethyl)Ether SCHEMBL27625390 0.93 TSHR (0.80) TSHRTHRBNAAAHTTPOLB
SCHEMBL6339685 0.93 TSHR (0.74) TSHRTHRBNAAAHTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116367818-A Cosmetic composition comprising an aminosilicone, a non-aminosilicone, and a nonionic associative polymer and cosmetic treatment method 莱雅公司 2023-06-30 CN claimed
US-7504094-B2 Cosmetic compositions containing a particular aminosilicone and a thickener, and uses thereof L'OREAL, S.A. (FR) 2009-03-17 US claimed
US-7300473-B2 Composition for dyeing keratin fibers with a cationic direct dye and a thickening polymer L'OREAL S.A. (FR) 2007-11-27 US claimed
US-20070154434-A1 Cosmetic compositions containing a particular aminosilicone and a thickener, and uses thereof L'OREAL S.A. 2007-07-05 US claimed
US-20030152542-A1 Cosmetic compositions containing a particular aminosilicone and a thickener, and uses thereof L'OREAL S.A. (FR) 2003-08-14 US claimed
US-20030147827-A1 Cosmetic compositions containing a particular aminosilicone and a thickener, and uses thereof L'OREAL S.A. (FR) 2003-08-07 US claimed
US-20030068291-A1 Cosmetic compositions comprising at least one silicone copolymer in aqueous emulsion and at least one associative thickener, and uses thereof L'OREAL S.A. (FR) 2003-04-10 US claimed
US-4211664-A MIXING ADSORBENT AND MAGNETIC PARTICLES IN A CROSSLINKABLE POLYMER ICI AUSTRALIA LIMITED (AU) 1980-07-08 US claimed
CN-118354749-A Kit and method for treating skin 莱雅公司 2024-07-16 CN disclosed
CN-118284402-A Cosmetic composition comprising a high amount of retinol 莱雅公司 2024-07-02 CN disclosed
CN-118201589-A Cosmetic composition comprising a high amount of ceramide-NP 莱雅公司 2024-06-14 CN disclosed
CN-118175983-A Hair treatment composition 莱雅公司 2024-06-11 CN disclosed
EP-4313319-A1 PROCESS FOR THE COSMETIC TREATMENT OF BRAIDED HAIR WITH A COMPOSITION COMPRISING A THICKENING POLYMER, A DERIVATIVE OF MENTHOL AND A PARTICULAR NON-IONIC SURFACTANT L'OREAL (FR) 2024-02-07 EP disclosed
CN-113194913-B Fragrance gel 莱雅公司 2024-01-02 CN disclosed
US-20020031484-A1 COSMETIC COMPOSITIONS COMPRISING AT LEAST ONE CATONIC POLYMER AND AT LEAST ONE NONIONIC ASSOCIATIVE POLYMER L'OREAL S.A. (FR) 2002-03-14 US disclosed
US-6280799-B1 Viscous substance discharging method using a viscous substance dispenser and pattern forming method using a viscous substance dispenser DAI NIPPON PRINTING CO., LTD. (JP) 2001-08-28 US disclosed
US-6080449-A EXCELLENT IN REDISPERSIBILITY, STORAGE STABILITY AND PRESS LIFE FUJI PHOTO FILM CO., LTD. (JP) 2000-06-27 US disclosed
US-4260552-A INSECTICIDES, HERBICIDES UNIROYAL, INC. (US) 1981-04-07 US disclosed
US-4211664-A MIXING ADSORBENT AND MAGNETIC PARTICLES IN A CROSSLINKABLE POLYMER ICI AUSTRALIA LIMITED (AU) 1980-07-08 US disclosed
US-4073775-A Powder coating composition ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1978-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030068291-A1 Cosmetic compositions comprising at least one silicone copolymer in aqueous emulsion and at least one associative thickener, and uses thereof KRT18, CUTA, DSG1 TSHR 2384/4885THRB 3800/4885NAAA 2410/4885
US-20020031484-A1 COSMETIC COMPOSITIONS COMPRISING AT LEAST ONE CATONIC POLYMER AND AT LEAST ONE NONIONIC ASSOCIATIVE POLYMER CAT, FABP4, ACR TSHR 3015/4885THRB 4619/4885NAAA 859/4885
US-20070154434-A1 Cosmetic compositions containing a particular aminosilicone and a thickener, and uses thereof CUTA, KRT18, DSG1 TSHR 3500/4885THRB 3076/4885NAAA 1455/4885
US-20030147827-A1 Cosmetic compositions containing a particular aminosilicone and a thickener, and uses thereof CUTA, KRT18, STMN1 TSHR 3520/4885THRB 3333/4885NAAA 1272/4885
US-20030152542-A1 Cosmetic compositions containing a particular aminosilicone and a thickener, and uses thereof CUTA, KRT18, PRMT8 TSHR 3663/4885THRB 3609/4885NAAA 1321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.