Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3983250 | 0.88 | GPR119 (0.41) | GPR119PIK3CDJAK3 | |
| SCHEMBL13690547 | 0.88 | GPR119 (0.57) | GPR119 | |
| SCHEMBL4059095 | 0.87 | SMN1; SMN2 (0.45) | GPR119RORC | |
| SCHEMBL4051113 | 0.86 | GPR119 (0.60) | GPR119RORC | |
| SCHEMBL3988442 | 0.86 | GPR119 (0.44) | GPR119PIK3CDJAK3PIK3CAMTOR | |
| SCHEMBL4048433 | 0.82 | RORC (0.41) | RORCATR | |
| SCHEMBL4060086 | 0.81 | RORC (0.46) | GPR119RORCPIK3CAMTORCPT2 | |
| SCHEMBL4055470 | 0.78 | GPR119 (0.45) | GPR119 | |
| SCHEMBL14141852 | 0.76 | GPR119 (0.48) | GPR119 | |
| SCHEMBL14218068 | 0.76 | AOC2 (0.43) | GPR119PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |