Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4305407 | 0.91 | ALDH1A1 (0.60) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL8757579 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL3943254 | 0.77 | ALDH1A1 (0.56) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL28326326 | 0.77 | HTT (0.66) | ALDH1A1RAB9AL3MBTL1HPGDKMT2A | |
| SCHEMBL4102754 | 0.77 | ALDH1A1 (0.61) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL3943250 | 0.77 | ALDH1A1 (0.56) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL2501666 | 0.77 | ALDH1A1 (0.56) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL2333531 | 0.77 | ALDH1A1 (0.56) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL31443947 | 0.77 | ALDH1A1 (0.56) | ALDH1A1TDP1NPC1RAB9ARECQL | |
| SCHEMBL238962 | 0.77 | L3MBTL1 (0.62) | ALDH1A1TDP1NPC1RAB9ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203879-A1 | ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME | BIOSIGHT LTD | 2009-08-13 | — | — | US | claimed |
| EP-1814908-A4 | ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME | BIOSIGHT LTD (IL) | 2009-07-01 | — | — | EP | claimed |
| EP-1814908-A1 | ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME | Biosight Ltd. (IL) | 2007-08-08 | — | — | EP | claimed |
| WO-2006054310-A1 | ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME | BIOSIGHT LTD. (IL) | 2006-05-26 | — | — | WO | claimed |
| US-8435800-B2 | Activated labeling reagents and methods for preparing and using the same | BIOSIGHT LTD. (IL) | 2013-05-07 | — | — | US | disclosed |
| US-20090203879-A1 | ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME | BIOSIGHT LTD | 2009-08-13 | — | — | US | disclosed |
| EP-1814908-A4 | ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME | BIOSIGHT LTD (IL) | 2009-07-01 | — | — | EP | disclosed |
| EP-1814908-A1 | ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME | Biosight Ltd. (IL) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006054310-A1 | ACTIVATED LABELING REAGENTS AND METHODS FOR PREPARING AND USING THE SAME | BIOSIGHT LTD. (IL) | 2006-05-26 | — | — | WO | disclosed |